2025
Kupke J, Loizou S, Bengtson CP, Sticht C, Oliveira AMM. (2025) Hippocampal DNA Methylation Promotes Contextual Fear Memory Persistence by Facilitating Systems Consolidation and Cortical Engram Stabilization. Biol Psychiatry. 98(5):394-403.
Commentary in Biol Psychiatry 98(5):370-372
Kupke J, Oliveira AMM. (2025) The molecular and cellular basis of memory engrams: Mechanisms of synaptic and systems consolidation. Neurobiol Learn Mem. 219:108057.
Zillich L, Artioli A, Pohořalá V, Zillich E, Stertz L, Belschner H, Jabali A, Frank J, Streit F, Avetyan D, Völker MP, Müller S, Hansson AC, Meyer TD, Rietschel M, Ladewig J, Spanagel R, Oliveira AMM, Walss-Bass C, Bernardi RE, Koch P, Witt SH. (2025) Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus. Nature Communications.16(1):3381
Commentary in Biol Psychiatry 98(5):370-372
Kupke J, Oliveira AMM. (2025) The molecular and cellular basis of memory engrams: Mechanisms of synaptic and systems consolidation. Neurobiol Learn Mem. 219:108057.
Zillich L, Artioli A, Pohořalá V, Zillich E, Stertz L, Belschner H, Jabali A, Frank J, Streit F, Avetyan D, Völker MP, Müller S, Hansson AC, Meyer TD, Rietschel M, Ladewig J, Spanagel R, Oliveira AMM, Walss-Bass C, Bernardi RE, Koch P, Witt SH. (2025) Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus. Nature Communications.16(1):3381
2024
Kupke J, Loizou S, Bengtson CP, Lutsik P, Plass C, Sticht C, Oliveira AMM (2024) Hippocampal DNA methylation promotes memory persistence by facilitating systems consolidation and cortical engram stabilisation. Neuropsychopharmacology. 49(10):1528-1539
Brito DVC*, Kupke J*, Sokolov R, Cambridge S, Both M, Bengtson CP, Rozov A, Oliveira AMM (2024) Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice. Molecular Psychiatry. 29(7):1929-1940
* Equal contribution
Brito DVC*, Kupke J*, Sokolov R, Cambridge S, Both M, Bengtson CP, Rozov A, Oliveira AMM (2024) Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice. Molecular Psychiatry. 29(7):1929-1940
* Equal contribution
2023
Brito DVC*, Kupke J*, Sokolov R, Cambridge S, Both M, Bengtson CP, Rozov A, Oliveira AMM (2023) Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice. BioRxiv.
* Equal contribution
Kupke J, Klimmt J*, Mudlaff F*, Schwab M, Sticht C, Oliveira AMM (2023) Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1. BioRxiv.
* Equal contribution
* Equal contribution
Kupke J, Klimmt J*, Mudlaff F*, Schwab M, Sticht C, Oliveira AMM (2023) Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1. BioRxiv.
* Equal contribution
2022
Brito DVC, Kupke J, Gulmez Karaca K, Oliveira AMM (2022) Regulation of neuronal plasticity by the DNA repair associated Gadd45 proteins. Current Research in Neurobiology. 3: 100031
2021
Gulmez Karaca K, Kupke J, Oliveira AMM (2021) Molecular and cellular mechanisms of engram allocation and maintenance. Brain Research Bulletin. 170:274-282
Gulmez Karaca K, Brito DCV, Kupke J, Zeuch B, Oliveira AMM (2021) Engram reactivation during memory retrieval predicts long-term memory performance in aged mice. Neurobiology of Aging. 101:256-261
Gulmez Karaca K, Brito DCV, Kupke J, Zeuch B, Oliveira AMM (2021) Engram reactivation during memory retrieval predicts long-term memory performance in aged mice. Neurobiology of Aging. 101:256-261
2020
Gulmez Karaca K, Kupke J, Brito DVC, Zeuch B, Thome C, Weichenhan D, Lutsik P, Plass C, Oliveira AMM (2020) Neuronal ensemble-specific DNA methylation strengthens engram stability. Nature Communications. 11(1):639
Brito DVC, Kupke J, Gulmez Karaca K, Zeuch B, Oliveira AMM (2020) Mimicking age associated Gadd45g dysregulation results in memory impairments in young adult mice. Journal of Neuroscience. 40(6):1197-1210
Brito DVC, Gulmez Karaca K*, Kupke J*, Frank L, Oliveira AMM (2020) MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus. Molecular Brain. 13(1):156
* Equal contribution
Brito DVC, Gulmez Karaca K, Kupke J, Mudlaff F, Zeuch B, Gomes R, Lopes LV, Oliveira AMM (2020) Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice. Neurobiology of Aging. 94:281-286
Brito DVC, Kupke J, Gulmez Karaca K, Zeuch B, Oliveira AMM (2020) Mimicking age associated Gadd45g dysregulation results in memory impairments in young adult mice. Journal of Neuroscience. 40(6):1197-1210
Brito DVC, Gulmez Karaca K*, Kupke J*, Frank L, Oliveira AMM (2020) MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus. Molecular Brain. 13(1):156
* Equal contribution
Brito DVC, Gulmez Karaca K, Kupke J, Mudlaff F, Zeuch B, Gomes R, Lopes LV, Oliveira AMM (2020) Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice. Neurobiology of Aging. 94:281-286
2019
Gulmez Karaca K, Brito DVC, Oliveira AMM (2019) MeCP2: a critical regulator of chromatin in neurodevelopment and adult brain function. International Journal of Molecular Sciences. 20(18):4577
Oliveira AMM *, Litke C*, Paldy E, Hagenston AM, Lu J, Kuner R, Bading H, Mauceri D (2019) Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2. Molecular Pain. 15:1-10
* Equal contribution
Oliveira AMM *, Litke C*, Paldy E, Hagenston AM, Lu J, Kuner R, Bading H, Mauceri D (2019) Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2. Molecular Pain. 15:1-10
* Equal contribution
2018
Gulmez Karaca K, Brito DCV, Zeuch B, Oliveira AMM (2018) Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation. Neurobiology of Learning and Memory. 149: 84-97
Cannella N*#, Oliveira AMM *#, Hemstedt T*, Lissek T, Buechler E, Bading H, Spanagel R (2018) Dnmt3a2 in the Nucleus Accumbens Shell is required for reinstatement of cocaine seeking. Journal of Neuroscience. 38(34): 7516-7528
* Equal contribution; # Corresponding authors
Cannella N*#, Oliveira AMM *#, Hemstedt T*, Lissek T, Buechler E, Bading H, Spanagel R (2018) Dnmt3a2 in the Nucleus Accumbens Shell is required for reinstatement of cocaine seeking. Journal of Neuroscience. 38(34): 7516-7528
* Equal contribution; # Corresponding authors
2017
Hemstedt TJ, Bengtson CP, Ramirez O, Oliveira AMM, Bading H (2017) Reciprocal interaction of dendrite geometry and nuclear calcium-VEGFD signaling gates memory consolidation and extinction. Journal of Neuroscience. 37(29):6946-6955
2016
Oliveira AMM (2016) DNA methylation: a permissive mark in memory formation and maintenance. Learning and Memory 23(10):587-593
Bas-Orth C*, Tan Y-W*, Oliveira AMM*, Bengtson CP, Bading H (2016) The calmodulin-binding transcription activator CAMTA1 is required for long-term memory formation in mice. Learning and Memory 23(6):313-321
* Equal contribution
Oliveira AMM, Hemstedt TJ, Freitag HE, Bading H (2016) Dnmt3a2: a hub for enhancing cognitive functions. Molecular Psychiatry 21: 1130-1136
Highlighted in Faculty of 1000 Biology
Bas-Orth C*, Tan Y-W*, Oliveira AMM*, Bengtson CP, Bading H (2016) The calmodulin-binding transcription activator CAMTA1 is required for long-term memory formation in mice. Learning and Memory 23(6):313-321
* Equal contribution
Oliveira AMM, Hemstedt TJ, Freitag HE, Bading H (2016) Dnmt3a2: a hub for enhancing cognitive functions. Molecular Psychiatry 21: 1130-1136
Highlighted in Faculty of 1000 Biology
2014 - 2005
Oliveira AMM, Bading H, Mauceri D (2014) Editorial of the Special Issue “Dysfunction of neuronal calcium signaling in aging and disease”. Cell & Tissue Research 357(2):381-383
Oliveira AMM, Hemstedt TJ, Bading H (2012) Rescue of aging-associated decline in Dnmt3a2 restores cognitive abilities. Nature Neuroscience 15(8): 1111-1113
News & Views in Nature Neuroscience 15(8): 1061-063
Highlighted in Nature 487:9; Faculty of 1000 Biology
Mauceri D, Freitag HE, Oliveira AMM, Bengtson CP, Bading H (2011) Nuclear Calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation. Neuron 71(1):117-130
Oliveira AMM and Bading H (2011) Calcium signaling in cognition and aging-dependent cognitive decline. Biofactors 37(3):168-174
Oliveira AMM, Estevez MA, Hawk JD, Grimes S, Brindle PK, Abel T (2011) Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments. Learning and Memory 18(3):161-169
Oliveira AMM, Hawk JD, Abel T, Havekes R (2010) Post-training reversible inactivation of the hippocampus enhances novel object recognition memory. Learning and Memory 17(3): 155-160
Oliveira AMM, Wood MA, McDonough C, Abel T (2007) Transgenic mice expressing a truncated form of p300 exhibit memory deficits. Learning and Memory 14(10): 564-572
Wood MA, Attner M, Oliveira AMM, Brindle PK, Abel T (2006) A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes. Learning and Memory 13(5): 609-617
Oliveira AMM, Abel T, Brindle PK, Wood MA (2006) Differential role for CBP and p300 CREB-binding domain in motor skill learning. Behavioral Neuroscience 120 (3): 724-729
Wood MA, Kaplan MP, Park A, Blanchard EJ, Oliveira AMM, Lombardi TL, Abel (2005) Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. Learning and Memory 12(2): 111-119
Steckler T, Lavreysen H, Oliveira AMM, Aerts N, van Craenendonck H, Prickaerts J, Megens A, Lesage ASJ (2005) Effects of mGlu1 receptor blockade on anxiety-related behaviour in the rat lick suppression test. Psychopharmacology 179(1): 198-206
Oliveira AMM, Hemstedt TJ, Bading H (2012) Rescue of aging-associated decline in Dnmt3a2 restores cognitive abilities. Nature Neuroscience 15(8): 1111-1113
News & Views in Nature Neuroscience 15(8): 1061-063
Highlighted in Nature 487:9; Faculty of 1000 Biology
Mauceri D, Freitag HE, Oliveira AMM, Bengtson CP, Bading H (2011) Nuclear Calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation. Neuron 71(1):117-130
Oliveira AMM and Bading H (2011) Calcium signaling in cognition and aging-dependent cognitive decline. Biofactors 37(3):168-174
Oliveira AMM, Estevez MA, Hawk JD, Grimes S, Brindle PK, Abel T (2011) Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments. Learning and Memory 18(3):161-169
Oliveira AMM, Hawk JD, Abel T, Havekes R (2010) Post-training reversible inactivation of the hippocampus enhances novel object recognition memory. Learning and Memory 17(3): 155-160
Oliveira AMM, Wood MA, McDonough C, Abel T (2007) Transgenic mice expressing a truncated form of p300 exhibit memory deficits. Learning and Memory 14(10): 564-572
Wood MA, Attner M, Oliveira AMM, Brindle PK, Abel T (2006) A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes. Learning and Memory 13(5): 609-617
Oliveira AMM, Abel T, Brindle PK, Wood MA (2006) Differential role for CBP and p300 CREB-binding domain in motor skill learning. Behavioral Neuroscience 120 (3): 724-729
Wood MA, Kaplan MP, Park A, Blanchard EJ, Oliveira AMM, Lombardi TL, Abel (2005) Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. Learning and Memory 12(2): 111-119
Steckler T, Lavreysen H, Oliveira AMM, Aerts N, van Craenendonck H, Prickaerts J, Megens A, Lesage ASJ (2005) Effects of mGlu1 receptor blockade on anxiety-related behaviour in the rat lick suppression test. Psychopharmacology 179(1): 198-206
